×
Login

Human DHFR protein

SKU
Name
Human DHFR protein
Size
50 ug
Price
$398.00
Qty

Human DHFR protein

Description
Recombinant protein from the full-length sequence of homo sapiens dihydrofolate reductase (DHFR), transcript variant 1 (NM_000791), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_000791; NP_000782; UniProt#: P00374; GeneID: 1719;
Synonyms
DHFRP1; DYR
Molecular Weight
21.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014].

Contact Us
View Storefront

Related Products


There's no citations at this moment.


There's no FAQs at this moment.


There's no reviews at this moment.