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Human RASGRP3 protein

SKU
Name
Human RASGRP3 protein
Size
50 ug
Price
$398.00
Qty

Human RASGRP3 protein

Description
Recombinant protein from the full-length sequence of homo sapiens RAS guanyl releasing protein 3 (RASGRP3), transcript variant 3 (NM_015376), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_015376; NP_056191; UniProt#: Q8IV61; GeneID: 25780;
Synonyms
GRP3; GRP3
Molecular Weight
78 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008].

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