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Human TBK1 protein

SKU
Name
Human TBK1 protein
Size
50 ug
Price
$398.00
Qty

Human TBK1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens TANK-binding kinase 1 (TBK1) (NM_013254), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_013254; NP_037386; UniProt#: Q9UHD2; GeneID: 29110;
Synonyms
NAK; T2K
Molecular Weight
83.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]

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