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Human AHCY protein

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Human AHCY protein
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Human AHCY protein

Description Recombinant protein from the full-length sequence of homo sapiens adenosylhomocysteinase (AHCY), transcript variant 1 (NM_000687), with a His tag.
Host Human cells
RefSeq Link NM_000687; NP_000678; UniProt#: P23526; GeneID: 191;
Synonyms adoHcyase; SAHH
Molecular Weight 47.5 kDa
Purity >90% by SDS-PAGE gel and Coomassie Blue staining
Applications Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)
Background S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].
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