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Human HOXD10 protein

SKU
Name
Human HOXD10 protein
Size
50 ug
Price
$398.00
Qty

Human HOXD10 protein

Description
Recombinant protein from the full-length sequence of homo sapiens homeobox D10 (HOXD10) (NM_002148), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_002148; NP_002139; UniProt#: P28358; GeneID: 3236;
Synonyms
Hox-4.4; HOX4; HOX4D; HOX4E
Molecular Weight
38.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008].

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