Human NR4A1 protein
Description
Recombinant protein from the full-length sequence of homo sapiens nuclear receptor subfamily 4 group A member 1 (NR4A1), transcript variant 1 (NM_002135), with a DYKDDDDK tag.
Synonyms
GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3
Molecular Weight
64.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein
(<1EU /µg)
Background
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
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