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Human IFI16 protein

SKU
Name
Human IFI16 protein
Size
50 ug
Price
$398.00
Qty

Human IFI16 protein

Description
Recombinant protein from the full-length sequence of homo sapiens interferon, gamma-inducible protein 16 (IFI16), transcript variant 2 (NM_005531), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_005531; NP_005522; UniProt#: Q16666; GeneID: 3428;
Synonyms
IFNGIP1; PYHIN2
Molecular Weight
81.9 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]

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