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Human CNOT11 protein

SKU
Name
Human CNOT11 protein
Size
50 ug
Price
$398.00
Qty

Human CNOT11 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens CCR4-NOT transcription complex subunit 11 (CNOT11) (NM_017546), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_017546; NP_060016; UniProt#: Q9UKZ1; GeneID: 55571;
Synonyms
C2orf29; C40
Molecular Weight
55 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function. [UniProtKB/Swiss-Prot Function]

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