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Human RAD52 protein

SKU
Name
Human RAD52 protein
Size
50 ug
Price
$398.00
Qty

Human RAD52 protein

Description
Recombinant protein from the full-length sequence of homo sapiens RAD52 homolog, DNA repair protein (RAD52), transcript variant 1 (NM_134424), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_134424; NP_602296; UniProt#: P43351; GeneID: 5893;
Synonyms
RP11-359B12.2
Molecular Weight
46 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014]

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