×
Login

Human PC protein

SKU
Name
Human PC protein
Size
Price
$398.00
Qty

Human PC protein

Description
Recombinant protein from the full-length sequence of homo sapiens pyruvate carboxylase (PC), transcript variant 2 (NM_022172), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_022172; NP_071504; UniProt#: P11498; GeneID: 5091;
Synonyms
PCB
Molecular Weight
127.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].

Contact Us
View Storefront

Related Products

Customers who come to this page are also interested in the following products:


There's no citations at this moment.


There's no FAQs at this moment.


There's no reviews at this moment.