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Human EIF4A2 protein

SKU
Name
Human EIF4A2 protein
Size
50 ug
Price
$398.00
Qty

Human EIF4A2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens eukaryotic translation initiation factor 4A2 (EIF4A2) (NM_001967), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_001967; NP_001958; UniProt#: Q14240; GeneID: 1974;
Synonyms
BM-010; DDX2B; eIF-4A-II; EIF4A; eIF4A-II; EIF4F
Molecular Weight
46.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. [UniProtKB/Swiss-Prot Function]

SDS-Page Image
Fig 1 : SDS-Page Image
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