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Human SQSTM1 protein

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Name
Human SQSTM1 protein
Size
50 ug
Price
$398.00
Qty

Human SQSTM1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens sequestosome 1 (SQSTM1), transcript variant 1 (NM_003900), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_003900; NP_003891; UniProt#: Q13501; GeneID: 8878;
Synonyms
A170; OSIL; p60; p62; p62B; PDB3; ZIP3
Molecular Weight
47.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]

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