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Human CUL4B protein

SKU
Name
Human CUL4B protein
Size
50 ug
Price
$398.00
Qty

Human CUL4B protein

Description
Recombinant protein from the full-length sequence of homo sapiens cullin 4B (CUL4B), transcript variant 1 (NM_003588), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_003588; NP_003579; UniProt#: Q13620; GeneID: 8450;
Synonyms
CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2
Molecular Weight
103.8 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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