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Human TRIM21 protein

SKU
Name
Human TRIM21 protein
Size
50 ug
Price
$398.00
Qty

Human TRIM21 protein

Description
Recombinant protein from the full-length sequence of homo sapiens tripartite motif containing 21 (TRIM21) (NM_003141), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_003141; NP_003132; UniProt#: P19474; GeneID: 6737;
Synonyms
RNF81; Ro/SSA; RO52; SSA; SSA1
Molecular Weight
54 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

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