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Human HDAC2 protein

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Human HDAC2 protein
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Price
$398.00
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Human HDAC2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens histone deacetylase 2 (HDAC2), transcript variant 1 (NM_001527), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_001527; NP_001518; UniProt#: Q92769; GeneID: 3066;
Synonyms
HD2; RPD3; YAF1
Molecular Weight
55.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].

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