Human CDC25C protein

Description

Recombinant protein from the full-length sequence of Homo sapiens cell division cycle 25C (CDC25C), transcript variant 1 (NM_001790), with a DYKDDDDK tag.

Host

Human Cells

Tags

DYKDDDDK

RefSeq Link

NM_001790; NP_001781; UniProt#: P30307; GeneID: 995;

Synonyms

CDC25; PPP1R60

Molecular Weight

53.2 kDa

Purity

>90% by SDS-PAGE gel and Coomassie Blue staining

Applications

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Formulation

Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Endotoxin

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Background

This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Dec 2015]