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Human YAP1 protein

SKU
Name
Human YAP1 protein
Size
50 ug
Price
$398.00
Qty

Human YAP1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens Yes associated protein 1 (YAP1), transcript variant 1 (NM_001130145), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_001130145; NP_001123617; UniProt#: P46937; GeneID: 10413;
Synonyms
COB1; YAP; YAP2; YAP65; YKI
Molecular Weight
54.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

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