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Human PYY protein

SKU
Name
Human PYY protein
Size
50 ug
 

Human PYY protein

Description
Recombinant protein from the full-length sequence of homo sapiens peptide YY (PYY) (NM_004160), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_004160; NP_004151; UniProt#: P10082; GeneID: 5697;
Synonyms
PYY-I; PYY1
Molecular Weight
11 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa. [provided by RefSeq, Feb 2016].

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