| Description | Recombinant protein from the full-length sequence of homo sapiens cancer susceptibility candidate 3 (CASC3) (NM_007359), with a His tag. |
| Host | Human cells |
| RefSeq Link | NM_007359; NP_031385; UniProt#: O15234; GeneID: 22794; |
| Synonyms | BTZ; MLN51 |
| Molecular Weight | 76.1 kDa |
| Purity | >90% by SDS-PAGE gel and Coomassie Blue staining |
| Applications | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Formulation | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg) |
| Background | The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008] |
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