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Human CASC3 protein

SKU
Name
Human CASC3 protein
Size
50 ug
Price
$398.00
Qty

Human CASC3 protein

Description
Recombinant protein from the full-length sequence of homo sapiens cancer susceptibility candidate 3 (CASC3) (NM_007359), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_007359; NP_031385; UniProt#: O15234; GeneID: 22794;
Synonyms
BTZ; MLN51
Molecular Weight
76.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]

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