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Human CASC3 protein

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Human CASC3 protein
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Human CASC3 protein

Description Recombinant protein from the full-length sequence of homo sapiens cancer susceptibility candidate 3 (CASC3) (NM_007359), with a His tag.
Host Human cells
RefSeq Link NM_007359; NP_031385; UniProt#: O15234; GeneID: 22794;
Synonyms BTZ; MLN51
Molecular Weight 76.1 kDa
Purity >90% by SDS-PAGE gel and Coomassie Blue staining
Applications Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)
Background The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]
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