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Human JAK3 protein

SKU
Name
Human JAK3 protein
Size
50 ug
Price
$398.00
Qty

Human JAK3 protein

Description
Recombinant protein from the full-length sequence of homo sapiens Janus kinase 3 (JAK3) (NM_000215), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_000215; NP_000206; UniProt#: P52333; GeneID: 3718;
Synonyms
JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
Molecular Weight
124.9 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]

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