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Human LGR5 protein

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Human LGR5 protein
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Price
$398.00
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Human LGR5 protein

Description
Recombinant protein from the full-length sequence of homo sapiens leucine rich repeat containing G protein-coupled receptor 5 (LGR5), transcript variant 1 (NM_003667), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_003667; NP_003658; UniProt#: O75473; GeneID: 8549;
Synonyms
FEX; GPR49; GPR67; GRP49; HG38
Molecular Weight
99.8 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015].

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