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Human CNOT7 protein

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Name
Human CNOT7 protein
Size
50 ug
Price
$398.00
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Human CNOT7 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens CCR4-NOT transcription complex subunit 7 (CNOT7), transcript variant 1 (NM_013354), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_013354; NP_037486; UniProt#: Q9UIV1; GeneID: 29883;
Synonyms
CAF1; Caf1a; hCAF-1
Molecular Weight
32.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]

SDS-Page Image
Fig 1 : SDS-Page Image
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