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Human PDE4B protein

SKU
Name
Human PDE4B protein
Size
50 ug
Price
$398.00
Qty

Human PDE4B protein

Description
Recombinant protein from the full-length sequence of homo sapiens phosphodiesterase 4B (PDE4B), transcript variant a (NM_002600), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_002600; NP_002591; UniProt#: Q07343; GeneID: 5142;
Synonyms
DPDE4; PDE4B5; PDEIVB
Molecular Weight
83.2 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

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