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Human LIG3 protein

SKU
Name
Human LIG3 protein
Size
50 ug
Price
$398.00
Qty

Human LIG3 protein

Description
Recombinant protein from the full-length sequence of homo sapiens ligase III, DNA, ATP-dependent (LIG3), transcript variant alpha (NM_013975), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_013975; NP_039269; UniProt#: P49916; GeneID: 3980;
Synonyms
LIG2
Molecular Weight
108.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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