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Human EIF4EBP1 protein

SKU
Name
Human EIF4EBP1 protein
Size
50 ug
Price
$398.00
Qty

Human EIF4EBP1 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) (NM_004095), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_004095; NP_004086; UniProt#: Q13541; GeneID: 1978;
Synonyms
4E-BP1; 4EBP1; BP-1; PHAS-I
Molecular Weight
12.4 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].

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