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Human KRAS protein

SKU
Name
Human KRAS protein
Size
50 ug
Price
$398.00
Qty

Human KRAS protein

Description
Recombinant protein from the full-length sequence of Homo sapiens KRAS proto-oncogene, GTPase (KRAS), transcript variant a (NM_033360), with a His tag.
Host
Human Cells
Source
RefSeq Link
NM_033360; NP_203524; UniProt#: P01116; GeneID: 3845;
Synonyms
C-K-RAS; c-Ki-ras2; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; RALD;
Molecular Weight
21.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008].

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