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Human IRF3 protein

SKU
Name
Human IRF3 protein
Size
50 ug
Price
$398.00
Qty

Human IRF3 protein

Description
Recombinant protein from the full-length sequence of homo sapiens interferon regulatory factor 3 (IRF3), transcript variant 1 (NM_001571), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_001571; NP_001562; UniProt#: Q14653; GeneID: 3661;
Synonyms
MGC94729; interferon regulatory factor 3
Molecular Weight
47 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].

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