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Human SMPD1 protein

SKU
Name
Human SMPD1 protein
Size
50 ug
Price
$398.00
Qty

Human SMPD1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens sphingomyelin phosphodiesterase 1 (SMPD1), transcript variant 1 (NM_000543), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_000543; NP_000534; UniProt#: P17405; GeneID: 6609;
Synonyms
ASM; ASMASE; NPD
Molecular Weight
65 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Formulated in a sterile solution of 0.1M Glycine, Tris-buffered saline, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010].

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