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Human NPTX2 protein

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Human NPTX2 protein
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Price
$398.00
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Human NPTX2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens neuronal pentraxin II (NPTX2) (NM_002523), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_002523; NP_002514; UniProt#: P47972; GeneID: 4885;
Synonyms
NARP; NP-II; NP2
Molecular Weight
46.9 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]

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