| Description | Recombinant protein from the full-length sequence of homo sapiens gelsolin (GSN), transcript variant 1 (NM_000177), with a His tag. |
| Host | Human cells |
| RefSeq Link | NM_000177; NP_000168; UniProt#: P06396; GeneID: 2934; |
| Synonyms | ADF; AGEL |
| Molecular Weight | 82.9 kDa |
| Purity | >90% by SDS-PAGE gel and Coomassie Blue staining |
| Applications | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Formulation | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg) |
| Background | The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
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