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Human GSN protein

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Human GSN protein
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Human GSN protein

Description Recombinant protein from the full-length sequence of homo sapiens gelsolin (GSN), transcript variant 1 (NM_000177), with a His tag.
Host Human cells
RefSeq Link NM_000177; NP_000168; UniProt#: P06396; GeneID: 2934;
Synonyms ADF; AGEL
Molecular Weight 82.9 kDa
Purity >90% by SDS-PAGE gel and Coomassie Blue staining
Applications Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg)
Background The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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