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Human PDE4A protein

SKU
Name
Human PDE4A protein
Size
50 ug
Price
$398.00
Qty

Human PDE4A protein

Description
Recombinant protein from the full-length sequence of Homo sapiens phosphodiesterase 4A (PDE4A), transcript variant 4 (NM_006202), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_006202; NP_006193; UniProt#: P27815; GeneID: 5141;
Synonyms
DPDE2; PDE4; PDE46
Molecular Weight
72 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].

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