Human cells

NM_001427; NP_001418; UniProt#: P19622; GeneID: 2020;

AUTS1, AUTS10;engrailed homolog 2; engrailed-2; engrailed homeobox 2

34 kDa

>90% by SDS-PAGE gel and Coomassie Blue staining

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008].