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Human TDO2 protein

SKU
Name
Human TDO2 protein
Size
50 ug
Price
$398.00
Qty

Human TDO2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens tryptophan 2,3-dioxygenase (TDO2) (NM_005651), with a DYKDDDDK tag.
Host
Human cells
Tags
DYKDDDDK
RefSeq Link
NM_005651; NP_005642; UniProt#: P48775; GeneID: 6999;
Synonyms
TDO; TO; TPH2; TRPO
Molecular Weight
47.7 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012].

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