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Human EARS2 protein

SKU
Name
Human EARS2 protein
Size
50 ug
 

Human EARS2 protein

Description
Recombinant protein from the full-length sequence of homo sapiens glutamyl-tRNA synthetase 2, mitochondrial (EARS2), transcript variant 1 (NM_001083614), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_001083614; NP_001077083; UniProt#: Q5JPH6; GeneID: 124454;
Synonyms
COXPD12; gluRS; MSE1
Molecular Weight
58.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015].

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