| Description | Recombinant protein from the full-length sequence of homo sapiens mitogen-activated protein kinase kinase kinase 15 (MAP3K15) (NM_001001671), with a His tag. |
| Host | Human cells |
| RefSeq Link | NM_001001671; NP_001001671; UniProt#: Q6ZN16; GeneID: 389840; |
| Synonyms | ASK3; bA723P2.3 |
| Molecular Weight | 147.3 kDa |
| Purity | >90% by SDS-PAGE gel and Coomassie Blue staining |
| Applications | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Formulation | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg) |
| Background | The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAPK) family. These family members function in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. This MAP3K protein plays an essential role in apoptotic cell death triggered by cellular stresses. [provided by RefSeq, Jul 2010]. |
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