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Human GSK3B protein

SKU
Name
Human GSK3B protein
Size
50 ug
Price
$398.00
Qty

Human GSK3B protein

Description
Recombinant protein from the full-length sequence of homo sapiens glycogen synthase kinase 3 beta (GSK3B), transcript variant 1 (NM_002093), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_002093; NP_002084; UniProt#: P49841; GeneID: 2932;
Synonyms
GSK3beta isoform; glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta
Molecular Weight
47.9 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

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