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Human TMX3 protein

SKU
Name
Human TMX3 protein
Size
50 ug
Price
$398.00
Qty

Human TMX3 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens thioredoxin related transmembrane protein 3 (TMX3), transcript variant 1 (NM_019022), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_019022; NP_061895; UniProt#: Q96JJ7; GeneID: 54495;
Synonyms
PDIA13; TXNDC10
Molecular Weight
51.7 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]

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