Human SDCBP2 protein

Description

Recombinant protein from the full-length sequence of Homo sapiens syndecan binding protein 2 (SDCBP2), transcript variant 2 (NM_015685), with a His tag.

Host

Human Cells

Tags

His

RefSeq Link

NM_015685; NP_056500; UniProt#: Q9H190; GeneID: 27111;

Synonyms

SITAC; SITAC18; ST-2

Molecular Weight

22.5 kDa

Purity

>90% by SDS-PAGE gel and Coomassie Blue staining

Applications

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Formulation

Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives

Endotoxin

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Background

The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031. [provided by RefSeq, Sep 2011].