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Human TRIM68 protein

SKU
Name
Human TRIM68 protein
Size
50 ug
Price
$398.00
Qty

Human TRIM68 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens tripartite motif containing 68 (TRIM68), transcript variant 1 (NM_018073), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_018073; NP_060543; UniProt#: Q6AZZ1; GeneID: 55128;
Synonyms
GC109; RNF137; SS-56; SS56
Molecular Weight
56.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a 'really interesting new gene' (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].

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