Human STXBP1 protein
Human STXBP1 protein
Description
Recombinant protein from the full-length sequence of homo sapiens syntaxin binding protein 1 (STXBP1), transcript variant 2 (NM_001032221), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
Synonyms
MUNC18-1; NSEC1; P67; RBSEC1; UNC18
Molecular Weight
67.4 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. [UniProtKB/Swiss-Prot Function]
Fig 1 : SDS-Page Image
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