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Human FBL protein

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Name
Human FBL protein
Size
Price
$398.00
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Human FBL protein

Description
Recombinant protein from the full-length sequence of homo sapiens fibrillarin (FBL) (NM_001436), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_001436; NP_001427; UniProt#: P22087; GeneID: 2091;
Synonyms
FIB; FLRN; RNU3IP1
Molecular Weight
33.6 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]

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