Human MIB1 protein
Recombinant protein from the full-length sequence of homo sapiens mindbomb E3 ubiquitin protein ligase 1 (MIB1) (NM_020774), with a DYKDDDDK tag.
DIP-1; DIP1; LVNC7; MIB; ZZANK2; ZZZ6
>90% by SDS-PAGE gel and Coomassie Blue staining
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]
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