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Human MIB1 protein

SKU
Name
Human MIB1 protein
Size
50 ug
Price
$398.00
Qty

Human MIB1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens mindbomb E3 ubiquitin protein ligase 1 (MIB1) (NM_020774), with a His tag.
Host
Human cells
Tags
His
RefSeq Link
NM_020774; NP_065825; UniProt#: Q86YT6; GeneID: 57534;
Synonyms
DIP-1; DIP1; LVNC7; MIB; ZZANK2; ZZZ6
Molecular Weight
110 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]

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