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Human COL6A1 protein

SKU
Name
Human COL6A1 protein
Size
50 ug
Price
$398.00
Qty

Human COL6A1 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens collagen type VI alpha 1 chain (COL6A1) (NM_001848), with a His tag.
Host
Human Cells
Tags
His
RefSeq Link
NM_001848; NP_001839; UniProt#: P12109; GeneID: 1291;
Synonyms
BTHLM1; OPLL; UCHMD1
Molecular Weight
108.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008].

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