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Human BECN1 protein

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Name
Human BECN1 protein
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Price
$398.00
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Human BECN1 protein

Description
Recombinant protein from the full-length sequence of homo sapiens beclin 1, autophagy related (BECN1), transcript variant 1 (NM_003766), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_003766; NP_003757; UniProt#: Q14457; GeneID: 8678;
Synonyms
ATG6; beclin1; VPS30
Molecular Weight
51.7 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

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