Human GSDME protein

Description

Recombinant protein from the full-length sequence of Homo sapiens gasdermin E (GSDME), transcript variant 1 (NM_004403), with a DYKDDDDK tag.

Host

Human Cells

Tags

DYKDDDDK

RefSeq Link

NM_004403; NP_004394; UniProt#: O60443; GeneID: 1687;

Synonyms

ICERE-1

Molecular Weight

54.4 kDa

Purity

>90% by SDS-PAGE gel and Coomassie Blue staining

Applications

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Formulation

Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Endotoxin

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

Background

Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].