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Human FXN protein

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Name
Human FXN protein
Size
Price
$398.00
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Human FXN protein

Description
Recombinant protein from the full-length sequence of homo sapiens frataxin (FXN), transcript variant 1 (NM_000144), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_000144; NP_000135; UniProt#: Q16595; GeneID: 2395;
Synonyms
CyaY; FA; FARR; FRDA; X25
Molecular Weight
18.8 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016].

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