Human cells

DYKDDDDK

NM_001386; NP_001377; UniProt#: Q16555; GeneID: 1808;

CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2

62.1 kDa

>90% by SDS-PAGE gel and Coomassie Blue staining

Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!

Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives

Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer&apos;s disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]