| Description | Recombinant protein from the full-length sequence of homo sapiens dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 (NM_001386), with a His tag. |
| Host | Human cells |
| RefSeq Link | NM_001386; NP_001377; UniProt#: Q16555; GeneID: 1808; |
| Synonyms | CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2 |
| Molecular Weight | 62.1 kDa |
| Purity | >90% by SDS-PAGE gel and Coomassie Blue staining |
| Applications | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Formulation | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | >Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg) |
| Background | This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |
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