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Human PIK3CG protein

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Name
Human PIK3CG protein
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Price
$398.00
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Human PIK3CG protein

Description
Recombinant protein from the full-length sequence of homo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (PIK3CG), transcript variant 1 (NM_002649), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_002649; NP_002640; UniProt#: P48736; GeneID: 5294;
Synonyms
p110gamma; p120-PI3K; PI3CG; PI3K; PI3Kgamma; PIK3
Molecular Weight
126.3 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015].

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