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Human ADAR protein

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Human ADAR protein
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Price
$398.00
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Human ADAR protein

Description
Recombinant protein from the full-length sequence of homo sapiens adenosine deaminase, RNA specific (ADAR), transcript variant 4 (NM_001025107), with a His tag.
Host
Human cells
Source
RefSeq Link
NM_001025107; NP_001020278; UniProt#: P55265; GeneID: 103;
Synonyms
ADAR1; AGS6; DRADA; DSH; DSRAD; G1P1; IFI-4; IFI4; K88DSRBP; P136
Molecular Weight
103.5 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010].

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