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Human USP7 protein

SKU
Name
Human USP7 protein
Size
50 ug
 

Human USP7 protein

Description
Recombinant protein from the full-length sequence of Homo sapiens ubiquitin specific peptidase 7 (USP7), transcript variant 1 (NM_003470), with a DYKDDDDK tag.
Host
Human Cells
Tags
DYKDDDDK
RefSeq Link
NM_003470; NP_003461; UniProt#: Q93009; GeneID: 7874;
Synonyms
HAUSP; TEF1
Molecular Weight
128.1 kDa
Purity
>90% by SDS-PAGE gel and Coomassie Blue staining
Applications
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Formulation
Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Endotoxin
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Background
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]

SDS-Page Image
Fig 1 : SDS-Page Image
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